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HiTrap MabSelect Family
HiTrap™ MabSelect™ and HiTrap MabSelect Xtra™ join HiTrap MabSelect SuRe™ (Superior Resistance) as members of the HiTrap family of prepacked columns for purification of monoclonal antibodies (MAbs).
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HiTrap MabSelect products provide:
- Increased binding capacity compared with other protein A media
- High purity in one step
- Convenient, prepacked 1-ml and 5-ml columns that are excellent for lab-scale use, screening of purification conditions, and process development
- Convenient operation with a syringe, a laboratory pump, or a chromatography system, such as ÄKTAdesign™
The matrix of MabSelect allows at least five-times higher flow rates to be used during scale-up as compared with conventional cross-linked agarose of similar porosity. HiTrap MabSelect Xtra uses the same recombinant protein A ligand as in MabSelect, but has a smaller particle size and greater porosity, which ensures increased dynamic binding capacity. HiTrap MabSelect SuRe features an alkali-stabilized protein A ligand that allows the usage of up to 0.5 M NaOH for cleaning-in-place (CIP). The ligand is immobilized on a rigid, high-flow agarose matrix.
For more information, please download the HiTrap MabSelect SuRe, HiTrap MabSelect, HiTrap MabSelect Xtra data file.
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