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Biotrak Assays for Airways Disease Asthma, COPD (Chronic Obstructive Pulmonary Disease) |  |
| Categories of Mediators | Biotrak™ Assays |
| Th2 cytokines - humoral immunity | IL-4, IL-5, IL-10, IL-13 |
| Eosinophil maturation | IL-3, GM-CSF, IL-5 |
| Chemoattractants - eosinophil infiltration | RANTES |
| Spasmogens - airway constriction | LTC4/D4/E4 |
| Chemoattractants | IL-5, LTB4, PAF, IL-8, MCP-1 |
| Complement Factors (Innate immunity - 1st line of defence vs allergen) | C3a, C4a, C5a |
| Anti-inflammatory agents | cAMP, cGMP |
| Metastasis in lung cancers (e.g. small cell lung cancer and primary pulmonary carcinomas) | MMP-2, MMP-10 |
| Elevated levels in lung cancers | TNF, IL-1, TGFα, IL-6, IL-8, IL-18, IL-4, IL-10, IFNγ |
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Th2 cytokines - humoral immunity
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Eosinophil maturation
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Chemoattractants - eosinophil infiltration
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Spasmogens - airway constriction
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Chemoattractants
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Complement Factors (Innate immunity - 1st line of defence vs allergen)
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Anti-inflammatory agents
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Metastasis in lung cancers (e.g. small cell lung cancer and primary pulmonary carcinomas)
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Elevated levels in lung cancers
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