Safety Issues to consider
Scintillation proximity assay (SPA) is a radioisotopic technique and, therefore, requires the use of radioactive material. You will find all the safety material in the material supplied with the product, this is just an overview.
Please follow the instructions relating to the safe handling and use of these and other materials. In addition, most countries have legislation governing the handling, use, storage, disposal, and transportation of radioactive materials. The safety information provided is intended to complement local regulations or codes of practice.
Please check with you RSO before purchasing the SPA product range and necessary components
More about;
Instructions about radioactive product use>
Yttrium compounds>
Poly (vinyl toluene) beads>
Instructions relating to the handling, use, storage, and disposal of radioactive materials
| 1. | Upon receipt, vials or ampoules containing radioactive material should be checked for contamination. All radioactive materials should be stored in specially designated areas and suitable shielding should be used where appropriate. Access to these areas should be restricted to authorized personnel only. |
| 2. | Only responsible persons in authorized areas should use radioactive material. Care should be taken to prevent ingestion or contact with skin or clothing. Protective clothing such as laboratory overalls, safety glasses, and gloves should be worn whenever radioactive materials are handled. Where this is appropriate, the operator should wear personal dosimeters to measure radiation dose to the body and fingers. |
| 3. | No smoking, drinking, or eating should be allowed in areas where radioactive materials are used. Avoid actions that could lead to the ingestion of radioactive materials, such as the pipetting of radioactive solutions by mouth. |
| 4. | Vials containing radioactive materials should not be touched by hand; wear thin surgical gloves as normal practice. Use forceps when handling vials containing "hard" beta emitters such as phosphorus-32 or gamma emitting labeled compounds. Ampoules likely to contain volatile radioactive compounds should be opened only in a well-ventilated fume cabinet. |
| 5. | Work should be carried out on a surface covered with absorbent material or in enamel trays of sufficient capacity to contain any spillage. Working areas should be monitored regularly. |
| 6. | Any spills of radioactive material should be cleaned immediately and all contaminated materials should be decontaminated or disposed of as radioactive waste via an authorized route. Contaminated surfaces should be washed with a suitable detergent to remove traces of radioactivity. |
| 7. | After use, all unused radioactive materials should be stored in specifically designated areas. Any radioactive product not required or any materials that have come into contact with radioactivity should be disposed of as radioactive waste via an authorized route. |
| 8. | Hands should be washed after using radioactive materials. Hands and clothing should be monitored using appropriate instruments to ensure that no contamination has occurred before leaving the designated area. If radioactive contamination is detected, hands should be washed again and rechecked. Any contamination persisting on hands and clothing should be reported to the responsible person so that suitable remedial actions can be taken. |
| 9. | Certain national/international organizations and agencies consider it appropriate to have additional controls during pregnancy. Users should check local regulations. |
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Yttrium compounds
Care should be taken to prevent ingestion, contact with skin, or inhalation of the dried powder. Use in a well-ventilated enclosure.
Wear suitable protective clothing such as laboratory overalls, safety glasses, and gloves. In the event of contact with skin or eyes wash the affected area thoroughly. If swallowed, take large amounts of water and seek medical attention.
The total yttrium compounds present in each pack is given in the appropriate pack leaflet.
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Poly (vinyl toluene) beads
Are not known to be harmful, but they should be considered as a potential irritant in dried form as a dust or powder. In this case the warning statement will be:
"This product contains one or more chemical substances supplied in small quantities. In the form supplied, these substances are not classified as dangerous within the meaning of the definitions of the Council of European Communities Directive 67/548/EEC and subsequent amendments.
All chemicals should be considered as potentially hazardous. We recommend that only those persons who have been trained in laboratory techniques handle these products and that they are used in accordance with the principles of good laboratory practice. Wear suitable protective clothing such as laboratory overalls, safety glasses, and gloves. Care should be taken to avoid contact with skin or eyes. In case of contact with skin or eyes wash immediately with water."
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New to Scintillation Proximity Assay (SPA)? Get started with the basics
Use theSPA selection guide to see the entire product range
Visit the literature section to view the published literature
Consult the technical support and customer service section for more support
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