Ion exchange chromatography

GE Healthcare has held a dominant position for ion exchange chromatography in biopharmaceutical production during recent decades. Media based on Sepharose™ Fast Flow are the industry standard in countless applications. More recent development has focused on rapid and cost-effective downstream processes for handling large volumes. The Capto™ line has been introduced with this specific task in mind.

Capto
Modern ion exchangers for high-productivity capture and intermediate purification. Faster purification and flexible process design enhance productivity.

Sepharose Fast Flow
Well-proven in industrial downstream processes. Used extensively for capture and intermediate purification of a wide range of biopharmaceuticals.

Sepharose Big Beads
For capture of large volumes of feed or viscous feedstocks at low back-pressures.

Sepharose High Performance
Ideal for intermediate purification and polishing applications. Use when resolution and capacity have priority.

Sepharose XL
Higher loading capacities for more productive capture from clarified feedstocks. Based on dextran-coated Sepharose Fast Flow.

SOURCE™
Mono-sized rigid polymeric beads deliver high resolution and have high chemical stability.

MacroCap SP
The ion exchanger for PEGylated proteins and other large molecules.

Sephadex™
High binding capacities for column or batch techniques. Based on cross-linked dextran.

Selection Kits
Quick and convenient small-scale media screening.