General information

Please describe your application, including modifications to any protocols, in sufficient detail so as to make it useful to other researchers. The described work must use an Amersham Biosciences product.
We are prepared to obtain permission from other publishers to reprint material.

Please submit your manuscript, in English, by email to Alex.Razdan@ge.com. Documents should be prepared using Microsoft™ Word.
Please include your complete mailing address, phone and fax numbers and email address with your submission. See below for additional information.

On receipt of your article, you will be contacted to discuss publication options for your material. If accepted, your material will be edited for length as necessary and to conform to the style of Discovery Matters. You will be consulted during the editing and layout process as necessary and you will receive a layout copy (“galley proof”) of your article for comments. You will be asked to sign and return a “permission to publish” form with your comments.

Article Guidelines

Abstract: 60–120 words

Body: 800 to 1000 words, 3 to 5 figures (two printed pages). Actual number of words per page depends on size and number of figures. More figures means fewer words. Word counts include references, but not abstract or figure captions. Articles will be edited for length and style to fit on two pages.

The article should describe applications and uses of new products or interesting uses of existing products. Include sufficient detail, including modifications to any protocols, to make the article useful to other researchers. If you are including material that has been published elsewhere, please identify the source so that we can obtain permission from the publisher to reprint the material.

Figures: Figures should be used to support key parts of the article, explain a method, show typical results, etc. Results should be clear and support the claim. See below for figure/image specifications and style guidelines for labels and figure captions.

References: Extensive use of references is encouraged. Please see below for reference style. Wherever possible, provide URLs for online abstracts (e.g PubMed) or full-text versions of the references. These will be used to provide links from the online version of your article to the referenced material.

Ordering Information: We will add ordering information for relevant products at the end of your article.

GE Healthcare
Style Guidelines

References
• Number references in the order of their occurrence in the text.
• Indicate references in text by numbers in round brackets ( ). Do not superscript.
• Personal communication, unpublished results or submitted references should not be included in the list of references.
• “In press” articles may be cited by number, but they must include the full list of authors, journal name and year of expected publication as well as the volume number, if known.
• Use the following format for references:

Reference number. Author last name, First initial. Middle initial. Title of article. Standard Journal Abbreviation Volume number, page number start–page number end (year).
Note the following:
1. List up to two authors. For two authors, separate authors’ names with “and.” If the reference includes more than two authors, list the first author followed by et al. (in italics).
2. Separate authors’ initials by a full stop (i.e. period) and a space. When required, place “Jr.” after the initials.
Example: Kelly, T. Jr.
3. Do not set authors’ names in all uppercase letters.
4. List the complete article title. Titles of articles should be regular, not italic text. Capitalize the first word of the title and write the title exactly as it appears in the work cited, ending with a full stop (period).
5. Italicize the standard journal abbreviation. There is no punctuation between the journal and the volume number except full stops (periods) associated with the journal abbreviation. Italicize book titles, and capitalize all main words.
6. Bold the volume number and follow it by a comma.
7. Include the inclusive page range for the citation. Separate the page numbers using an en dash (–), not a hyphen (-). Do not preface the page range with p, pp., pgs., and so on, except as noted below for books.
8. Set the publication year in round brackets (i.e. parentheses). There is no other punctuation between the page numbers and the year.
9. Use a full stop (period) at the end of the reference.

Abstracts/posters at conferences
1. Barton, B. G. et al. Novel uses for His-tagged fusion vectors, in Abstracts of the 94th General Meeting of the American Society for Microbiology 1994, American Society for Microbiology, Washington, D.C., abstr. H-249, p. 244 (1994).
Note: Abstracts published in a conference proceedings are treated like book citations. The abstract number and page number in the proceedings are required.
Books
Entire book with author
1. Gallagher, S. R., Current Protocols in Molecular Biology Vol. 2, John Wiley and Sons, Inc., New York (1995).
2. Kelley, R. F. and Winkler, M. E., Genetic Engineering Vol. 12, Plenum Press, New York (1990).

Entire book with editor
3. Ausubel, F. A., et al., eds., Current Protocols in Molecular Biology Vol. 2, John Wiley and Sons, Inc., New York (1995).
4. Setlow, J. K., ed., Genetic Engineering Vol. 12, Plenum Press, New York (1990).
Part of book with author
5. Gallagher, S. R. 2-D gel electrophoresis, in Current Protocols in Molecular Biology Vol. 2 (Ausubel, F. A., et al., eds.), John Wiley and Sons, Inc., New York, p. 10.2.2 (1995).
6. Kelley, R. F. and Winkler, M. High-throughput screening of recombinant GST fusion protein, in Genetic Engineering Vol. 12 (Setlow, J. K., ed.), Plenum Press, New York, pp. 1–19 (1990).
Note: In book references, abbreviate volume to Vol. (in bold, followed by a full stop). Also, preface page numbers with either a p. for a single page or pp. for multiple pages.
Journal articles
Journal articles with one author
1. Owicki, J. C. Fluorescence polarization and anisotropy in highthroughput screening: perspectives and primer. J. Biomol. Sreening 5, 297–306 (2000).
Journal articles with two authors
2. Yana, I. and Weiss, S. J. Regulation of MT1-MMP activation by proprotein convertases. Mol. Biol. Cell 11, 2387–2401 (2000).
Journal articles with three or more authors
3. Sato H. et al. A matrix metalloproteinase expressed on the surface of invasive tumor cells. Nature 370, 61–65 (1994).
Note: Do not use a comma between the author’s initial and et al.

Specifications for figures (e.g. photos, autoradiograms, etc.)
• Please submit digitized images or camera-ready art.
• Digitized images must be submitted as TIFF or EPS files.
• Digitized images need to have been scanned or acquired with a minimum image width of 1000 pixels.
• If camera-ready art or digitized images are not available, please submit original hard data (e.g. gel photographs, autoradiograms, etc.). If original data is submitted, it will be digitized using a high-resolution scanner and the original data will be returned to you.
• For photographs, please indicate figure number and top of photo on the backside of the photograph.
• For all other figures, do not write on the original. Indicate cropping, labels, etc. on a photocopy of the figure.

Specifications for diagrams, graphs, bar charts, illustrations, etc.
• Please submit electronic files or camera-ready art.
• Electronic files can be submitted as Adobe Illustrator files only. Software incompatibilities prevent us from accepting other electronic versions of your illustrations.
• For questions concerning figures/illustrations, please contact Editor—Discovery Matters (see below).

Figure/illustration style guidelines
• All figures must be referred to in the text. Figures should be numbered with arabic numerals in the order in which they are cited.
• For figure captions (legends), use a short description of the figure as a title. Figure captions should be concise but contain sufficient detail to understand the figure without reading the text. Complete details should appear in the Materials and Methods section of the document. If the document does not contain a Materials and Methods section, the figure caption should contain information about the samples, sample volumes, special preparation or handling, primer sequences, amplification conditions, gel running conditions, reaction conditions, etc
• Conclusions about the results presented in the figure should not be included in the caption but should be discussed in the body of the article.
• For all gel result figures (agarose, polyacrylamide, sequencing, etc.), use descriptive labels for the lanes rather than lane numbers, when space permits.

Table style guidelines
• All tables must be cited in the text. Tables should be numbered with arabic numerals in the order in which they are cited.
• Organize tables so that all rows are the same type of data sets, usually identified by the principal independent variable (experiment number, sample number, volume or extract added).
• Omit columns in which all rows have the same value. If it is not discussed in the text, the value may be included in a footnote to the table.
• Values in a column should all be in the same units (mg or ng, not mixed mg and ng) with the unit indicated in round brackets (i.e. parentheses) at the top of the column, not appended to each value in the column. If it is not possible to use the same units for all values in a column, then append the correct unit to each value in the column.

If you have any questions about how to submit material, please contact: Alex Razdan, Editor—Discovery Matters email: Alex.Razdan@ge.com telephone +46 18 612 0312